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GSK106(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK106(hydrochloride)图片
CAS NO:1652591-82-6
规格:98%
分子量:438
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline.
CAS:1652591-82-6
分子式:C24H27N5O.HCl
分子量:438
纯度:98%
存储:Store at -20°C

Background:

Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199 . It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC50s >100 µM). See the Structural Genomics Consortium (SGC) website for more information on both GSK484 and GSK106.