CAS NO: | 5370-01-4 |
规格: | 98% |
分子量: | 215.72 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
Background:
Mexiletine (hydrochloride) (KOE-1173 (hydrochloride)) is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound.
[1]. Desaphy JF, et al. Effect of mexiletine on sea anemone toxin-induced non-inactivating sodium channels of rat skeletal muscle: a model of sodium channel myotonia. Neuromuscul Disord. 1999 May;9(3):182-9. [2]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+-activated K+ channel current in guinea pig ventricular cells. Naunyn Schmiedebergs Arch Pharmacol. 1998 Dec;358(6):641-8.