Gastrointestinal peptide that stimulates pancreatic and biliary secretion
CAS：121028-49-7
分子式：C129H216N42O42
分子量：3027.38
纯度：98%
存储：Store at -20°C

Background:

Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.

Secretin (33-59), rat inhibits adrenocorticotropic hormone (ACTH) release, and selectively suppresses the glucocorticoid response to ACTH of dispersed zona fasciculata-reticularis (ZF/R) cells[1]. Secretin retrograde messenger to facilitate GABA transmission in the rat cerebellum[2].

参考文献:
[1]. Nussdorfer GG, et al. Secretin, glucagon, gastric inhibitory polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus- pituitary-adrenal axis. Peptides. 2000 Feb;21(2):309-24.
[2]. Ng SS, et al. Secretin as a neuropeptide. Mol Neurobiol. 2002 Aug;26(1):97-107.