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NNC45-0781
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NNC45-0781图片
CAS NO:207277-66-5
规格:98%
分子量:415.52
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
NNC45-0781是一种组织选择性的雌激素(estrogen)部分激动剂。
CAS:207277-66-5
分子式:C27H29NO3
分子量:415.52
纯度:98%
存储:Store at -20°C

Background:

NNC45-0781 is a tissue-selective estrogen partial-agonist.



NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group[1].


[1]. Bury PS, et al. Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor. Bioorg Med Chem. 2002 Jan;10(1):125-45.