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(2S)-Octyl-α-hydroxyglutarate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1391194-64-1
规格:98%
分子量:260.33
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
200mg电议

产品介绍
A modified form of S-isomer 2-Hydroxyglutarate
CAS:1391194-64-1
分子式:C??H??O?
分子量:260.33
纯度:98%
存储:Store at -20°C

Background:

(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.


Treatment of IDH1-WT HeLa cells with (2S)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells[1].


Reference:


[1]. Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).