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PF-04937319
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF-04937319图片
CAS NO:1245603-92-2
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

PF-04937319 (PF04937319) is a novel and potent glucokinase activator (EC50 = 154.4 μM) with the potential to be used for the treatment of type 2 diabetes mellitus. It was designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs. PF-04937319 is a glucokinase activator which is under development for the treatment of type 2 diametes mellitus. Glucose-phosphorylating enzyme, glucokinase (GK) plays a major role in glucose homeostasis primarily through its regulatory actions in pancreatic β-cells and liver hepatocytes. Conversion of glucose to glucose-6-phosphate by GK promotes glycogen synthesis in liver hepatocytes, and insulin release in the pancreatic β-cells.

纯度:≥98%

CAS:1245603-92-2