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Cyclosporin A-Derivative 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyclosporin A-Derivative 1图片
CAS NO:1487360-85-9
规格:98%
分子量:1364.5
包装与价格:
包装价格(元)
10mg电议
50mg电议
1mg电议
5mg电议

产品介绍
Cyclosporin A-Derivative 1 是环孢菌素 A 衍生的结晶中间体,来自专利 WO 2013167703 A1。Cyclosporin A 是一种免疫抑制剂,能够与亲环蛋白结合并抑制钙调磷酸酶。
CAS:1487360-85-9
分子式:C65H118BF4N11O14
分子量:1364.5
纯度:98%
存储:Store at -20°C

Background:

Cyclosporin A-Derivative 1 is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.


Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporine A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate[1].



[1]. Fabrice Gallou, et al. Process for the manufacture of cyclic undecapeptides. WO 2013167703 A1.