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Amifampridine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amifampridine图片
CAS NO:54-96-6
规格:98%
分子量:109.13
包装与价格:
包装价格(元)
200mg电议
500mg电议
100mg电议

产品介绍
Amifampridine (3,4-Diaminopyridine) 可作用于罕见的肌肉疾病。
CAS:54-96-6
分子式:C5H7N3
分子量:109.13
纯度:98%
存储:Store at -20°C

Background:

Amifampridine (3,4-Diaminopyridine) is a drug, predominantly in the treatment of a number of rare muscle diseases.Target: OthersAmifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate. A 2005 systematic review from the Cochrane Collaboration found some data favouring its use in LEMS. Amifampridine is also used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. From Wikipedia.




[1]. http://en.wikipedia.org/wiki/3,4-Diaminopyridine#cite_note-4