Zabofloxacin hydrochloride (DW-224a) 是一种新型氟萘啶酮喹诺酮，被认为是临床试验的有效抗菌候选物。Zabofloxacin hydrochloride (DW-224a) 具有抗革兰氏阳性病原体的优良活性，包括金黄色葡萄球菌 (S. aureus)，化脓性链球菌(S. pyrigenes)和肺炎链球菌(S. pneumonia)。Zabofloxacin hydrochloride (DW-224a) 被认为是治疗喹诺酮类易感和喹诺酮类耐药性淋病的替代药物。
CAS：623574-00-5
分子式：C19H21ClFN5O4
分子量：437.85
纯度：98%
存储：Store at -20°C

Background:

Zabofloxacin hydrochloride (DW-224a) is a novel fluoronaphthyridone quinolone that is considered a potent antibacterial candidate for clinical trials.Zabofloxacin hydrochloride (DW-224a) has excellent activity against gram-positive pathogens including Steptococcus aureus (S. aureus), Streptococcus pyogenes (S. pyrigenes), and S. pneumonia.Zabofloxacin hydrochloride (DW-224a) is considered as an alternative candidate for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].

[1]. Park HS, et al. Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae. Molecules. 2016 Nov 17;21(11). pii: E1562.