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Phosphatidylglycerols(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phosphatidylglycerols(sodium salt)图片
CAS NO:383907-64-0
规格:98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
500mg电议

产品介绍
Phosphatidylglycerol is a naturally occurring anionic phospholipid and a constituent of plant, animal, and bacterial cell membranes.
CAS:383907-64-0
分子量:
纯度:98%
存储:Store at -20°C

Background:

Phosphatidylglycerol is a naturally occurring anionic phospholipid and a constituent of plant, animal, and bacterial cell membranes. It is less abundant than phosphatidylethanolamine? in prokaryotes and eukaryotes and phosphatidylcholine? in eukaryotes. It is formed via a reaction between CDP-diglyceride with L-α-glycerol 3-phosphate followed by dephosphorylation and is a metabolic precursor of cardiolipin. Phosphatidylglycerol species containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote proliferation of murine keratinocytes, respectively. Phosphatidylglycerol is the second largest lipid component of mammalian lung surfactant, comprising 10% of the lipids, and levels are decreased in the lung surfactant of infants with respiratory distress syndrome. Phosphatidylglycerols (egg) is a mixture of phosphatidylglycerols isolated from egg with various fatty acyl groups at the sn-1 and sn-2 positions.


参考文献:
[1]. Ohtsuka, T., Nishijima, M., and Akamatsu, Y. A somatic cell mutant defective in phosphatidylglycerophosphate synthase, with impaired phosphatidylglycerol and cardiolipin biosynthesis J. Biol. Chem. 268(30), 22908-22913 (1993).
[2]. Furse, S. Is phosphatidylglycerol essential for terrestrial life? J. Chem. Biol. 10(1), 1-9 (2016).
[3]. Xie, D., Seremwe, M., Edwards, J.G., et al. Distinct effects of different phosphatidylglycerol species on mouse keratinocyte proliferation PLoS One 9(9), e107119 (2014).