| CAS NO: | 1872387-43-3 |
| 规格: | 98% |
| 分子量: | 552.58 |
| 包装 | 价格(元) |
| 2mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
DC661
A potent PPT1 inhibitorBackground:
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1].
DC661 (0.1 and 10 μM) accumulates autophagic vesicles in melanoma cells[1].
Reference:
[1]. Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.
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