CAS NO: | 63775-95-1 |
规格: | 98% |
分子量: | 1188.6 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
Cyclosporin B is a minor cyclopeptide metabolite produced by T. polysporum and other deuteromycota with diverse biological activities. It inhibits the growth of T lymphoma cells in a concentration-dependent manner. It is toxic to mosquito (C. pipiens) larvae (LC50 = 3.0 μg/ml). Cyclosporin B also inhibits P-glycoprotein (P-gp) activity in vitro with an IC50 value of 4.7 μM.