GSK2200150A是通过高通量表型筛选确定的一种抗结核剂。对H37Rv的MIC是0.38μM.
CAS：1443138-53-1
分子式：C20H23NO3S
分子量：357.47
纯度：98%
存储：Store at -20°C

Background:

GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.

GSK2200150A is a novel antimycobacterial agent against Mycobacterium tuberculosis.The activities of GSK2200150A containing the spirocycle core are determined against the virulent M.tuberculosis strain (H37Rv) with MIC of 0.38 μM[1].

[1]. Badiola KA, et al. Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in OpenScience. PLoS One. 2014 Dec 10;9(12):e111782.