Background:

Peucedanol has been isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan [1]. The maximum test concentration of peucedanolat (125 μM) showed no significant influence on cell viability. P-gp related efflux mechanism was associated with the transport of peucedanol [1].

Reference:
[1].  Yang Y F, Xu W, Song W, et al. Transport of twelve coumarins from AngelicaePubescentis Radix across a MDCK-pHaMDR cell monolayer—An in vitro model for blood-brain barrier permeability[J]. Molecules, 2015, 20(7): 11719-11732.