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AL 6598
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AL 6598图片
CAS NO:170291-06-2
规格:98%
分子量:431
包装与价格:
包装价格(元)
10mg电议
500ug电议
1mg电议
5mg电议

产品介绍
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma.
CAS:170291-06-2
分子式:C23H39ClO5
分子量:431
纯度:98%
存储:Store at -20°C

Background:

Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 µM and demonstrates an EC50 value of 0.80 µM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.