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K252b
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
K252b图片
CAS NO:99570-78-2
规格:98%
分子量:453.5
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
K252b is an indolocarbazole isolated from the actinomycete Nocardiopsis, first described as an inhibitor of protein kinase C.
CAS:99570-78-2
分子式:C26H19N3O5
分子量:453.5
纯度:98%
存储:Store at -20°C

Background:

K252b is an indolocarbazole isolated from the actinomycete Nocardiopsis, first described as an inhibitor of protein kinase C. However, as this compound does not freely pass through the cell membrane, it is used to inhibit extracellular kinases (ectokinases) of cells in culture. K252b inhibits receptor-mediated degranulation from basophil-like RBL-2H3 cells (IC50 = 0.5 μg/ml) and human basophils. This extracellular inhibitor is also used in comparison studies with the closely related, cell-permeable inhibitor K252a, particularly in studies of neuronal differentiation.