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Magnoflorine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Magnoflorine图片
CAS NO:2141-09-5
规格:98%
分子量:342.4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Magnoflorine is an alkaloid and a major constituent of S.
CAS:2141-09-5
分子式:C20H24NO4
分子量:342.4
纯度:98%
存储:Store at -20°C

Background:

Magnoflorine is an alkaloid and a major constituent of S. acutum that has diverse biological activities. It reduces hemolysis induced by lysophosphatidylcholine (LPC), but not NaCl, in a rat erythrocyte suspension when used at concentrations ranging from 0.01 to 10 μM. Magnoflorine (10 μM) induces intracellular chloride influx in neuroblastoma cells, an effect that is reversed by the GABAA receptor antagonist bicuculline . It reduces TNF-α-induced NF-κB expression as well as production of IL-6 and IL-8 in BEAS-2B cells. In vivo, magnoflorine (20 mg/kg, i.p.) improves short- and long-term memory acquisition in a passive avoidance test in a mouse model of scopolamine-induced memory impairment.