diABZI STING agonist-1 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂。
CAS：2138299-33-7
分子式：C42H51N13O7
分子量：849.94
纯度：98%
存储：Store at -20°C

Background:

diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. STING[1].

diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.