GTP cyclohydrolase I (GCH1) inhibitor and blocks NO production
CAS：56-06-4
分子式：C4H6N4O
分子量：126.12
纯度：98%
存储：Store at -20°C

Background:

2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production[1].

参考文献:
[1]. Sung YJ, et al. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol. 1994 Feb;16(2):101-8.