Bacoside A3 is a triterpenoid saponin first isolated from B.
CAS：157408-08-7
分子式：C47H76O18
分子量：929.1
纯度：98%
存储：Store at -20°C

Background:

Bacoside A3 is a triterpenoid saponin first isolated from B. monniera. Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro. An extract containing bacoside A3 and bacopaside II (4 and 1.3 ug/mg extract, respectively) administered for eight days at a dose of 10-30 mg/kg reduces opioid withdrawal-induced depression in mice using the forced swim test. Bacoside A3 also has antioxidant properties following liver and kidney damage induced by street heroin in rats.