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AD 0261
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AD 0261图片
CAS NO:145600-69-7
规格:98%
分子量:451.55
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
AD0261是一种自由基清除剂,能够有效抑制脂质过氧化物和超氧化物阴离子的产生。
CAS:145600-69-7
分子式:C27H31F2N3O
分子量:451.55
纯度:98%
存储:Store at -20°C

Background:

AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.


AD 0261 displays strong inhibitory action on the generation of lipid peroxides (IC50=0.022 μM) and superoxide anions (IC50= 0.9-4.0 μM). AD 0261 inhibits cytokine release and/or production from PHA-P-stimulated lymphocytes in a dose-dependent manner. AD 0261 inhibits all parameters which are indicative of lymphocyte activation with 50% inhibition being achieved in a range of 1-10 μM. AD 0261 suppresses ornithine decarboxylase activity, the IC50 value being around 1.0 μM[1].



[1]. M. Sugiura, et al. Effect of the novel radical scavenger AD0261 on lymphocyte activation. Information Research. Agents and Actions. August 1994, Volume 41, Supplement 2, pp C216-C218.