CAS NO: | 2244895-42-7 |
规格: | 98% |
分子量: | 406.48 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
Background:
IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.