CAS NO: | 52179-44-9 |
规格: | 98% |
分子量: | 302.3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Background:
Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.
参考文献:
[1]. Song, Y.C., Huang, W.Y., Sun, C., et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides Biol. Pharm. Bull. 28(3), 506-509 (2005).
[2]. Hormazabal, E., Schmeda-Hirschmann, G., Astudillo, L., et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum Z. Naturforsch. C. 60(1-2), 11-21 (2005).