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N-(n-Butyl)deoxygalactonojirimycin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-(n-Butyl)deoxygalactonojirimycin图片
CAS NO:141206-42-0
规格:98%
分子量:219.3
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of α-D-galactosidase.
CAS:141206-42-0
分子式:C10H21NO4
分子量:219.3
纯度:98%
存储:Store at -20°C

Background:

N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of α-D-galactosidase. It has also been shown to prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders by inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 µM) without affecting α-glucosidase I and II or β-glucocerebrosidase (IC50s >1 mM). This compound has been used to sensitize cultured chronic lymphocytic leukemia cells to the chemotherapeutic agents cladribine , chlorambucil , and fludarabine .