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17α,20β-Dihydroxy-4-pregnen-3-one
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
17α,20β-Dihydroxy-4-pregnen-3-one图片
CAS NO:1662-06-2
规格:98%
分子量:332.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An endogenous, maturation-inducing steroid
CAS:1662-06-2
分子式:C21H32O3
分子量:332.5
纯度:98%
存储:Store at -20°C

Background:

17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persian sturgeon oocytes has been shown to effectively induce germinal vesicle breakdown, an essential step during oocyte maturation.1 Gonadotropin-releasing hormone and the gonadotropins, follicle-stimulating hormone and luteinizing hormone, have been shown to stimulate the production of 17α,20β-DHP either in vivo or in vitro.[2] 17α,20β-DHP has also been reported to influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts.[1]


Reference:
[1]. Milla, S., Terrien, X., Sturm, A., et al. Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout Oncorhynchus mykiss spermiation: Implication with 17alpha, 2βdihydroxyprogesterone on the milt fluidity? Reproductive Biology and Endocrinology 6, 19 (2008).
[2]. Planas, J.V., and Swanson, P. Maturation-associated changes in the response of the salmon testis to the steroidogenic actions of gonadotropins (GTH I and GTH II) in vitro. Biology of Reproduction 52(3), 697-704 (1995).