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CAY10452
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10452图片
CAS NO:170569-87-6
规格:98%
分子量:367.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2.
CAS:170569-87-6
分子式:C16H12F3N3O2S
分子量:367.3
纯度:98%
存储:Store at -20°C

Background:

Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2. However, many COX inhibitors also show an antitumor, pro-apoptotic activity that is distinct from COX inhibition - celecoxib is an example. CAY10452 is a celecoxib analog that retains potent, selective COX-2 inhibitory activity (IC50 = 32 nM), but does not induce apoptosis in prostate cancer cell lines even at 100 uM. CAY10452 is thus a clean, selective tool for the inhibition of COX-2.