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Mestranol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mestranol图片
CAS NO:72-33-3
包装:100mg
规格:98%
市场价:428元
分子量:310.43

产品介绍
Estrogen used in contraceptives
CAS:72-33-3
分子式:C21H26O2
分子量:310.43
纯度:98%
存储:Store at -20°C

Background:

Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.Target: Estrogen Receptor/ERRMestranol is absorbed very rapidly from the digestive tract and maximum plasma levels are attained in 1-4 hours, the majority at 1-2 hours. Detectable levels of mestranol are present 24 hours postingestion in 58% of subjects after a 50 μg dose and in 79% after a 100 μg dose. At all dose levels, highest plasma mestranol levels and area under the curve of plasma levels (AUC) occurred in Sri Lankan women, and lowest plasma levels in Nigerian women, even when corrected for body surface differences [1].


参考文献:
[1]. Goldzieher, J.W., T.S. Dozier, and A. de la Pena, Plasma levels and pharmacokinetics of ethynyl estrogens in various populations: II. Mestranol. Contraception, 1980. 21(1): p. 17-27.