| CAS NO: | 344930-95-6 |
| 规格: | 98% |
| 分子量: | 556.63 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
Background:
High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50= 3.9 nM). Displays species-selectivity (Kivalues are 0.017, 1.70, 3.01, 58 and > 100 nM?for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID50= 2.8 mg/kg) and reduces infarct size in anin vivoacute model of coronary ischemia-reperfusion injury. Orally active.
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