CAS NO: | 146062-45-5 |
包装: | 5mg |
规格: | 98% |
市场价: | 8452元 |
分子量: | 370.4 |
Background:
Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone . Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.