Gilvocarcin M is an antibiotic originally isolated from S.
CAS：77879-89-1
分子式：C26H26O9
分子量：482.5
纯度：98%
存储：Store at -20°C

Background:

Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 µg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 µg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400 mg/kg. Gilvocarcin M intercalates into bacteriophage PM2 DNA. It is toxic to rats with an intravenous LD50 value of 450 mg/kg.