| CAS NO: | 1793059-58-1 |
| 规格: | 98% |
| 分子量: | 451.82 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 25mg | 电议 |
Tinostamustine HCl
An alkylatlng histone-deacetylase inhibitor (HDACi) fusion moleculeBackground:
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents.
Reference:
[1].? Mehrling T, Chen Y. The Alkylating-HDAC Inhibition Fusion Principle: Taking
[2]. Chemotherapy to the Next Level with the First in Class Molecule EDO-S101.
[3]. Anticancer Agents Med Chem. 2015;16(1):20-8. PubMed PMID: 25980817.
m.cnreagent.com