Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS.
CAS：1246304-34-6
分子式：C18H30D7NO2
分子量：306.5
纯度：98%
存储：Store at -20°C

Background:

Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.