Sisomicin is a broad-spectrum aminoglycoside antibiotic originally isolated from M.
CAS：32385-11-8
分子式：C19H37N5O7
分子量：447.5
纯度：98%
存储：Store at -20°C

Background:

Sisomicin is a broad-spectrum aminoglycoside antibiotic originally isolated from M. inyoensis. It is active against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa among others (MICs = 0.01-0.75 µg/ml) but is less active against P. multocida and V. coli (MICs = 7.5 and 2.4 µg/ml, respectively). Sisomicin is protective against Gram-positive and Gram-negative bacterial infections in mice with 50% protective dose (PD50s) values ranging from 0.5 to 6 mg/kg.