| CAS NO: | 10129-56-3 |
| 包装: | 50mg |
| 规格: | 98% |
| 市场价: | 3254元 |
| 分子量: | 240.52 |
Background:
PETCM is an activator of caspase-3 [1].
Caspase-3 is a member of the cysteine-aspartic acid protease family and interacts with caspase-8 and caspase-9. Sequential activation of caspases plays an important role in cell apoptosis.
In HeLa S-100 cell cytosol, PETCM activated caspase-3 in a dose-dependent way and induced apoptosome formation. PETCM (0.2 mM) caused Apaf-1 shifted to a size of
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