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JMV3002
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JMV3002图片
CAS NO:925239-03-8
规格:98%
分子量:586.7
包装与价格:
包装价格(元)
5mg电议
100ug电议
500ug电议
1mg电议

产品介绍
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis.
CAS:925239-03-8
分子式:C35H34N6O3
分子量:586.7
纯度:98%
存储:Store at -20°C

Background:

Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 µg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 µg/kg.