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Rp-8-bromo-Cyclic AMPS(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rp-8-bromo-Cyclic AMPS(sodium salt)图片
CAS NO:925456-59-3
规格:98%
分子量:446.1
包装与价格:
包装价格(元)
5mg电议
500ug电议
1mg电议

产品介绍
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.
CAS:925456-59-3
分子式:C10H10BrN5O5PS .Na
分子量:446.1
纯度:98%
存储:Store at -20°C

Background:

Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.