N-acetyl Histamine is a histamine metabolite that is formed via acetyl-CoA-dependent N-acetylation of histamine by AANATL7 in D.
CAS：673-49-4
分子式：C7H11N3O
分子量：153.2
纯度：98%
存储：Store at -20°C

Background:

N-acetyl Histamine is a histamine metabolite that is formed via acetyl-CoA-dependent N-acetylation of histamine by AANATL7 in D. melanogaster, polyamine N-acetyltransferase in F. hepatica, and the arylalkylamine N-acetyltransferases aaNAT2 and aaNAT5b in A. aegypti. It selectively inhibits sweet-almond β-glucosidase over yeast α-glucosidase in vitro (Kis = 0.035 and 20 mM, respectively). It also inhibits human glutaminyl cyclase (IC50 = 17 μM). N-acetyl Histamine has no effect on eosinophil activity and has been used as a negative control for histamine mediation of anaphylaxis.