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Olodaterol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Olodaterol图片
CAS NO:868049-49-4
规格:98%
分子量:386.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Olodaterol is a selective agonist of β2-adrenergic receptors (β2-ARs; EC50s = 97.7 and 2,725 nM for human β2- and β1-ARs, respectively).
CAS:868049-49-4
分子式:C21H26N2O5
分子量:386.4
纯度:98%
存储:Store at -20°C

Background:

Olodaterol is a selective agonist of β2-adrenergic receptors (β2-ARs; EC50s = 97.7 and 2,725 nM for human β2- and β1-ARs, respectively). In vivo, olodaterol completely reverses acetylcholine-induced bronchoconstriction without cardiovascular side effects in guinea pigs. It also exhibits dose-dependent bronchoprotection in a beagle model of acetylcholine-induced bronchoconstriction for a period of 24 hours, indicating potential for once-daily dosing. Formulations containing olodaterol have been used to treat bronchoconstriction associated with chronic obstructive pulmonary disease.