BILB-1941 is a HCV NS5B polymerase inhibitor potentially for the treatment of HCV infection. BILB-1941 is the first thumb pocket 1 NS5B inhibitor that demonstrated antiviral activity in patients chronically infected with genotype 1 HCV. BILB 1941 monotherapy demonstrated antiviral activity against HCV genotype 1, but gastrointestinal intolerance precluded testing of higher doses. References: Beaulieu PL, Anderson PC, Bethell R, Bos M, Bousquet Y, Brochu C, Cordingley MG, Fazal G, Garneau M, Gillard JR, Kawai S, Marquis M, McKercher G, Poupart MA, Stammers T, Thavonekham B, Wernic D, Duan J, Kukolj G. Discovery of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for the potential treatment of chronic hepatitis C virus infection. J Med Chem. 2014 Dec 11;57(23):10130-43. doi: 10.1021/jm501532z. PubMed PMID: 25393851.

纯度：≥98%

CAS：494856-61-0