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CMI977(LDP977)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CMI977(LDP977)图片
CAS NO:175212-04-1
规格:98%
分子量:322.33
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
CMI977是一种有效的5-Lipoxygenase(5-LO)抑制剂。
CAS:175212-04-1
分子式:C16H19FN2O4
分子量:322.33
纯度:98%
存储:Store at -20°C

Background:

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.


CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.



[1]. Xiong Cai, et al. Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. Org. Proc. Res. Dev., 1999, 3 (1), pp 73-76.