Extracted?from?whole herb of Polygala japonicaHoutt.;Store?the?product?in?sealed,?cool?and?dry?condition
CAS：882664-74-6
分子式：C53H86O23
分子量：1090.24
纯度：98%
存储：Store at -20°C

Background:

Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway [1].

参考文献:
[1]. Yan WF , et al. The molecular mechanism of polygalasaponin F-mediated decreases in TNFα: emphasizing the role of the TLR4-PI3K/AKT-NF-κB pathway. J Asian Nat Prod Res. 2015;17(6):662-70.