Ac-DEVD-AMC is a fluorogenic substrate that can be cleaved specifically by caspase-3.
CAS：169332-61-0
分子式：C30H37N5O13
分子量：675.6
纯度：98%
存储：Store at -20°C

Background:

Ac-DEVD-AMC is the Caspase-3 substrate.

Ac-DEVD-AMC is the caspase-3 substrate and could be used to monitor intracellular caspase-3 activity[1].The AMC moiety is highest at 2 h (area?=5.6±1.8), the AMC peak area for Ac-DEVD-AMC incubated without lung specimen (substrate alone) for 6 h is relatively small[2].

参考文献:
[1]. Ahmed R Alsuwaidi, et al. Bioenergetics of murine lungs infected with respiratory syncytial virus. Virol J. 2013; 10: 22.
[2]. Ahmed R Alsuwaidi, et al. Lung tissue bioenergetics and caspase activity in rodents. BMC Res Notes. 2013; 6: 12.