3-?Dehydrotrametenolic acid，分离于茯苓菌核，是一种乳酸脱氢酶 (LDH) 抑制剂。3-?Dehydrotrametenolic acid 促进体外脂肪细胞分化，在体内起胰岛素增敏剂的作用。3-?Dehydrotrametenolic acid 诱导细胞凋亡，具有抗癌活性。
CAS：29220-16-4
分子式：C30H46O3
分子量：454.68
纯度：98%
存储：Store at -20°C

Background:

3-?Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-?Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-?Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2]. Lactate dehydrogenase [1]

[1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.