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CMX001
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CMX001图片
CAS NO:444805-28-1
规格:98%
分子量:561.69
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
Broad spectrum antiviral drug
CAS:444805-28-1
分子式:C27H52N3O7P
分子量:561.69
纯度:98%
存储:Store at -20°C

Background:

CMX001 is a broad spectrum antiviral agent [1].


CMX001 has been reported to be active in vitro against a broad range of viruses from all five families of dsDNA viruses infecting human with EC50 values of 0.02μM, 0.0004μM, 17μM , 0.045μM and 0.07μM for Adenovirus, Herpesvirus, Papillomavirus, Polyomavirus and Orthopoxvirus, respectively. In addition, CMX001 has been revealed to arrest disease progression by inhibiting viral DNA replication and thereby reducing viral burden. Apart from these, initial studies has been demonstrated the efficacy of CMX001 for pre-exposure and post-exposure prophylaxis in mouse, rabbit, cynomolgus monkeys and human [1].


参考文献:
[1]Lanier R1, Trost L, Tippin T, Lampert B, Robertson A, Foster S, Rose M, Painter W, O'Mahony R, Almond M, Painter G.Development of CMX001 for the Treatment of Poxvirus Infections. Viruses. 2010 Dec; 2(12):2740-2762.