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CCMI
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CCMI图片
CAS NO:917837-54-8
规格:98%
分子量:388.25
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR)
CAS:917837-54-8
分子式:C19H15Cl2N3O2
分子量:388.25
纯度:98%
存储:Store at -20°C

Background:

CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1].


CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs[1].


参考文献:
[1]. Ng HJ, et al. Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8059-64. Epub 2007 Apr 30.