CAS NO: | 180694-97-7 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
Mimopezil, formerly known as ZT-1 and Debio-9902, is an acetylcholinesterase (AChE) inhibitor potentially for the treatment of Alzheimer's disease (AD). ZT-1 is a pro-drug that is rapidly absorbed and converted into huperzine A, and ZT-1 is well tolerated in healthy Chinese volunteers. Huperzine A extracted from the Chinese herb Huperzia serrata (Thunb) Trev is a novel reversible and selective AChE inhibitor. References: Jia JY, Zhao QH, Liu Y, Gui YZ, Liu GY, Zhu DY, Yu C, Hong Z. Phase I study on the pharmacokinetics and tolerance of ZT-1, a prodrug of huperzine A, for the treatment of Alzheimer's disease. Acta Pharmacol Sin. 2013 Jul;34(7):976-82. doi: 10.1038/aps.2013.7. PubMed PMID: 23624756; PubMed Central PMCID: PMC4002618.
纯度:≥98%
CAS:180694-97-7