您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > PF 04418948
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PF 04418948
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF 04418948图片
CAS NO:1078166-57-0
规格:98%
分子量:409.41
包装与价格:
包装价格(元)
10mg电议
50mg电议
500mg电议
1g电议

产品介绍

EP2 receptor antagonist
CAS:1078166-57-0
分子式:C23H20FNO5
分子量:409.41
纯度:98%
存储:Store at -20°C

Background:

PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.

参考文献:
[1]. af Forselles KJ, et al. In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist. Br J Pharmacol. 2011 Dec;164(7):1847-1856.
[2]. Birrell MA, et al. Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor. Br J Pharmacol. 2013 Jan;168(1):129-138.