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MitoPQ
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MitoPQ图片
CAS NO:1821370-28-8
规格:98%
分子量:954.5
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
MitoPQ is comprised of a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.
CAS:1821370-28-8
分子式:C39H46N2P.3I
分子量:954.5
纯度:98%
存储:Store at -20°C

Background:

MitoPQ is comprised of a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.[1] Driven by membrane potential, it accumulates selectively in the mitochondrial matrix where it produces superoxide by redox cycling at the flavin site of complex I.[1] Thus, MitoPQ selectively increases superoxide production within mitochondria and can be used as a tool either in cells or in vivo to investigate the role of mitochondrial superoxide in pathology and redox signaling.[1]


Reference:
[1]. Robb, E.L., Gawel, J.M., Aksentijevic, D., et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radical Biology & Medicine 89, 883-894 (2015).