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Cirsimaritin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cirsimaritin图片
CAS NO:6601-62-3
规格:98%
分子量:314.29
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Cirsimaritin可以较弱的靶向结合GABAA受体上的苯二氮平位点,并拥有抗抑郁、抗焦虑、抗接种等活性。
CAS:6601-62-3
分子式:C17H14O6
分子量:314.29
纯度:98%
存储:Store at -20°C

Background:

Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.



Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds[1].


[1]. Abdelhalim A, et al. Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis. J Pharm Pharm Sci. 2015;18(4):448-59.