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Cnidicin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cnidicin图片
CAS NO:14348-21-1
规格:98%
分子量:354.4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Cnidicin 是一种来自 Angelica koreana 根的香豆素,可抑制肥大细胞脱颗粒和 RAW 264.7 细胞产生一氧化氮 (NO).
CAS:14348-21-1
分子式:C21H22O5
分子量:354.4
纯度:98%
存储:Store at -20°C

Background:

Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].


Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1].



[1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4.